Total synthesis of tetronolide, the aglycon of tetrocarcins

DOI: 10.1016/S0040-4039(00)93498-1

Source and publish data:

Tetrahedron Letters p. 4925 - 4928 (1991)

Update date:2022-08-04

Topics:

Authors:

Takeda, Kei

Kawanishi, Eiji

Nakamura, Hitoshi

Yoshii, Eiichi

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Article abstract of DOI:10.1016/S0040-4039(00)93498-1

The first total synthesis of tetronolide (1) has been achieved via coupling of spirotetronate 3 with octahydronaphthalene aldehyde 17 and subsequent macrocyclization of ω-sulfone-α-aldehyde 2, leading to confirmation of the absolute configuration of 1.

Full text of DOI:10.1016/S0040-4039(00)93498-1

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