Formation of 3-azetidin-2-ones: Stereocontrolled Formal Approach to (+/-)-Thienamycin and (+/-)-β-(Hydroxyalkyl)aspartic Acid Derivatives

DOI: 10.1021/jo00031a044

Source and publish data:

Journal of Organic Chemistry p. 1571 - 1579 (1992)

Update date:2022-09-26

Topics:

Authors:

Palomo, Claudio

Aizpurua, Jesus M.

Urchegui, Raquel

Iturburu, Miren

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Article abstract of DOI:10.1021/jo00031a044

Reaction between (+/-)-β-(dimethylphenylsilyl)alkanoyl chlorides and imines of glyoxylic esters provided a route to (+/-)-cis-3-<1'-(dimethylphenylsilyl)ethyl>-4-alkoxycarbonyl β-lactams, while addition of the Fleming's silylcuprate reagent to methyl crot

Full text of DOI:10.1021/jo00031a044

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