
Bioorganic and Medicinal Chemistry Letters p. 4173 - 4178 (2012)
Update date:2022-07-30
Topics:
Roberts, Lee R.
Brady, Kevin
Brown, Amy
Davey, Doreen
Feng, Lijin
Huang, Hanhua
Liu, Dingguo
Malet, Laia
McMurray, Gordon
Phelan, Anne
Saunders, Ken
Bhat, Abhijit
Small peptidic kappa agonists were covalently linked to the reactive lysine of the CovX antibody to create compounds having potent activity at the kappa receptor with greatly extended half-life when compared to the parent peptide as exemplified by compoun
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