1524
L. Chu, F.-L. Qing
SPECIAL TOPIC
1H NMR (300 MHz, CDCl3): δ = 4.69–4.61 (m, 2 H), 1.97–1.94 (m,
4 H), 1.78–1.74 (m, 4 H), 1.68–1.58 (m, 4 H), 1.55–1.48 (m, 2 H),
1.42–1.23 (m, 6 H).
13C NMR (100 MHz, CDCl3): δ = 119.99 (dq, J = 284.6 Hz, J =
307.9 Hz), 79.77 (d, J = 7.0 Hz), 33.60 (d, J = 3.2 Hz), 33.05 (d, J =
4.9 Hz), 24.81, 23.20 (d, J = 3.5 Hz).
19F NMR (282 MHz, CDCl3): δ = –73.35 (d, 2JP,F = 122 Hz, 3 F).
31P{1H} NMR (CDCl3): δ = –4.60 (q, 2JP,F = 123 Hz).
HRMS (ESI): m/z [M + Na]+ calcd for C13H22F3NaO3P: 337.1151;
O. A.; Escudero-Adan, E. C.; Belmonte, M. M.; Grushin, V.
V. Angew. Chem. Int. Ed. 2011, 50, 3793.
(4) Recent examples for trifluoromethylation of C–H bonds,
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Liu, L. J. Am. Chem. Soc. 2011, 133, 15300. (e) Wang, X.;
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(5) (a) Umemoto, T.; Ishihara, S. J. Am. Chem. Soc. 1993, 115,
2156. (b) Umemoto, T.; Adachi, K.; Ishihara, S. J. Org.
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found: 337.1148.
Acknowledgment
National Natural Science Foundation of China (21072028,
20832008) and National Basic Research Program of China
(2012CB21600) are gratefully acknowledged for funding this work.
Supporting Information for this article is available online at
g
iSutpor
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