The synthesis of 5′-deoxyjuglomycin a and 5′ -methoxyjuglomycin a

Article abstract of DOI:10.1016/0040-4039(91)80184-8

The Syntheses of 5′-deoxyjuglomycin A (17 and 5′-methoxyjuglomycin A (18) are reported in which the key step involves eerie ammonium nirate oxidative cleavage of the furo(3,2-b)naphtho [2,1-d]furans (7,8). The synthesis of 5′-methoxyjuglomycin A (18) represents a formal synthesis of juglomycins A and B (1) and (2).