Stereocontrolled syntheses of some conformationally restricted analogs of serotonin

DOI: 10.1016/S0040-4020(01)96188-5

Source and publish data:

Tetrahedron p. 8653 - 8662 (1991)

Update date:2022-08-04

Topics:

Authors:

Ghosh, Arun

Wang, Wuyi

Freeman, Jeremiah P.

Althaust, John S.

VonVoigtlander, Philip F.

Scahill, Terrence A.

Mizsak, Stephen A.

Szmuszkovicz, Jacob

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Article abstract of DOI:10.1016/S0040-4020(01)96188-5

Syntheses of serotonin analogs 2 and 3 are described including a case of retention in the Mitsunobu reaction. An unusual stereoselectivity in a reductive animation sequence is also described. Dopamine and serotonin activity of the eight analogs has been d

Full text of DOI:10.1016/S0040-4020(01)96188-5

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