Enantioselective reactions of 2-bromopropanamides with primary, secondary, and tertiary amines. Synthesis of some alaninamides

Article abstract of DOI:10.1016/S0957-4166(00)82009-1

Enantiomeric 2-bromopropanamides react with primary, secondary, or tertiary aliphatic amines in toluene at room temperature, yielding the corresponding secondary or tertiary amino, or quaternary ammonium amide. If the reacting amines are good nucleophiles