COBALT(II) CHLORIDE CATALYSED CONVERSION OF ALLYLIC ALCOHOLS TO REARRANGED ALLYLIC AMIDES

Article abstract of DOI:10.1016/0040-4039(91)80456-G

Secondary and tertiary allylic alcohols can be converted to the corresponding allylically rearranged amides and acetates in presence of a catalytic quantity of cobalt(II) chloride and acetic anhydride in acetonitrile.Tertiary alcohols undergo complete rearrangement whereas the secondary ones yield a mixture of regioisomers.