Synthesis of diastereomeric 3,6-diaminobicyclo[3.1.0]hexane derivatives: A stereocomplementary approach

Article abstract of DOI:10.1055/s-1991-28406

Diastereomeric (1α,3β,5α,6β)- and (1α,3α,5α,6β)-diaminobicyclo [3.1.0]hexane-6-carbonitriles 12 and 16 were synthesized with high stereoselectivity from 1,4-cyclohexanedione monoacetal 6 via chloroenamines 17 and 18, respectively. The sequence of reaction