2,2'-Disubstituted biphenyls: Synthesis and suppressive effect against carbon tetrachloride-induced liver injury

DOI: 10.1248/cpb.42.62

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 62 - 66 (1994)

Update date:2022-08-03

Topics: Synthesis

Authors:

Kondo Kondo

Takahashi

Ohmizu Ohmizu

Matsumoto

Taguchi Taguchi

Iwasaki Iwasaki

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Article abstract of DOI:10.1248/cpb.42.62

2,2'-Disubstituted biphenyl compounds (1-15) were synthesized by using the Ullmann coupling reaction as a key step. The suppressive effect of these compounds against CCl₄-induced liver injuries in mice was evaluated. An unsymmetrical biphenyl (

Full text of DOI:10.1248/cpb.42.62

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