Intramolecular Cycloadditions of Keteniminium Salts. A Practical Asymmetric Synthesis of Prostaglandins

Article abstract of DOI:10.1016/S0957-4166(00)80017-8

The intramolecular <2 + 2> cycloaddition of keteniminium salt 5 derived from (2S,5S)-dimethylpyrrolidine is the key step of a short synthetic route toward prostaglandins.