Tetrahedron p. 10023 - 10034 (1991)
Update date:2022-08-03
Topics:
Garcia
Pascual
Borras
Andreu
Fos
Mauleon
Carganico
Arcamone
A series of new glycerophospholipids, bearing a short-chain carboxylic acid in position sn-1 and phosphocholine or phosphoserine in postion sn-3 of glycerol, have been prepared in good overall yields. Compound 11, 1-0-(6-carboxyhexyl)-sn-glycero-3-phosphoserine, a strict analog of the structure proposed for modulator, has been synthesized in a stereoselective way from (R)-1,2-isopropylideneglycerol 1.
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Doi:10.1016/S0960-894X(00)00102-5
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