Synthesis of new ether glycerophospholipids structurally related to modulator

DOI: 10.1016/S0040-4020(01)96051-X

Source and publish data:

Tetrahedron p. 10023 - 10034 (1991)

Update date:2022-08-03

Topics:

Authors:

Garcia Garcia

Pascual Pascual

Borras Borras

Andreu Andreu

Fos Fos

Mauleon Mauleon

Carganico

Arcamone

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Article abstract of DOI:10.1016/S0040-4020(01)96051-X

A series of new glycerophospholipids, bearing a short-chain carboxylic acid in position sn-1 and phosphocholine or phosphoserine in postion sn-3 of glycerol, have been prepared in good overall yields. Compound 11, 1-0-(6-carboxyhexyl)-sn-glycero-3-phosphoserine, a strict analog of the structure proposed for modulator, has been synthesized in a stereoselective way from (R)-1,2-isopropylideneglycerol 1.

Full text of DOI:10.1016/S0040-4020(01)96051-X

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Product name:1-O-(6-carboxylhexyl)glycero-3-phosphoserine

Cas No:139239-73-9

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