Efficient synthesis of 2'-deoxynucleoside 3'-C-phosphonates: Reactivity of geminal hydroxyphosphonate moiety

Article abstract of DOI:10.1080/15257770008035038

In this report we present a novel, simple way for the synthesis of 3'-C-phosphonate derivatives of all four basic 2'-deoxynucleosides in both fully protected and deprotected forms. The reactivity of the geminal hydroxy phosphonate moiety located at the 3'

Full text of DOI:10.1080/15257770008035038

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Efficient Synthesis of 2′-
Deoxynucleoside 3′-C-
Phosphonates: Reactivity of Geminal
Hydroxyphosphonate Moiety
Śárka Králíková a , Miloś Buděšínský a , Milena Masojídková a & Ivan
Rosenberg a
a Institute of Organic Chemistry and Biochemistry, Academy of
Sciences of the Czech Republic , 166 10, Prague, 6, Czech Republic
Published online: 05 Nov 2010.
To cite this article: Śárka Králíková , Miloś Buděšínský , Milena Masojídková & Ivan Rosenberg
(2000) Efficient Synthesis of 2′-Deoxynucleoside 3′-C-Phosphonates: Reactivity of Geminal
Hydroxyphosphonate Moiety, Nucleosides, Nucleotides and Nucleic Acids, 19:7, 1159-1183, DOI:
10.1080/15257770008035038
To link to this article: http://dx.doi.org/10.1080/15257770008035038
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