A reductive acidolysis final deprotection strategy in solid phase peptide synthesis based on safety-catch protection

DOI: 10.1248/cpb.45.18

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 18 - 26 (1997)

Update date:2022-08-06

Topics: Deprotection Reductive acidolysis

Authors:

Kimura, Tooru

Fukui, Toshio

Tanaka, Shigeki

Akaji, Kenichi

Kiso, Yoshiaki

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Article abstract of DOI:10.1248/cpb.45.18

A reductive acidolysis final deprotection strategy in solid phase peptide synthesis was developed using a new safety-catch type of semi- permanent protecting groups and new linkers which were derived from 4- methylsulfinylbenzyl protection. This new strat

Full text of DOI:10.1248/cpb.45.18

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