New Aspects in the Regioselective Functionalization of Furans. Synthesis of Tri- and Tetrasubstituted Furan Derivatives.

DOI: 10.1016/S0040-4020(01)80587-1

Source and publish data:

Tetrahedron p. 149 - 158 (1992)

Update date:2022-07-30

Topics:

Authors:

Dominguez, Carmen

Csaky, Aurelio G.

Plumet, Joaquin

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Article abstract of DOI:10.1016/S0040-4020(01)80587-1

Application of directed ortho metalation reaction and electrophilic aromatic substitution allows for the regioselective synthesis of tri- and tetrasubstituted furans, thus superseding classical de novo furan construction modes. Key Words: Furan functionalization; imidazolidine; oxazoline; electrophilic aromatic substitution; 1J(13C-H)

Full text of DOI:10.1016/S0040-4020(01)80587-1

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