A Simple Asymmetric Synthesis of 2-Substituted Pyrrolidines and 5-Substituted Pyrrolidinones

DOI: 10.1021/jo00032a012

Source and publish data:

Journal of Organic Chemistry p. 1656 - 1662 (1992)

Update date:2022-08-06

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Authors:

Burgess, Laurence E.

Meyers, A. I.

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Article abstract of DOI:10.1021/jo00032a012

An efficient procedure for the preparation of the title compounds in high enantiomeric purity has been realized starting from 3-acylpropionic acids.Stereoselective reduction of chiral bicyclic lactams 2a-h, prepared from the corresponding γ-keto acid and

Full text of DOI:10.1021/jo00032a012

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