Tetrahedron p. 9909 - 9924 (1996)
Update date:2022-08-05
Topics:
Funaki, Ikuo
Thijs, Lambertus
Zwanenburg, Binne
The synthesis of 4,5 disubstituted-3 amino-γ-lactams from N- substituted aziridinecarboxamides is described. Bicyclic aziridine derivatives were obtained from 1-N-Boc-aziridinecarboxamides under kinetically controlled conditions. Oxiranecarboxamides showed similiar behavior and gave 3-hydroxy-lactams.
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Doi:10.1021/acs.orglett.9b02893
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