Palladium-mediated phosphine-dependent chemoselective bisallylic alkylation leading to spirocarbocycles

Article abstract of DOI:10.1002/anie.201204629

Cycles everywhere: The selectivity in the transformations of 1,3-diones to carbocycles by palladium-catalyzed bisallylic alkylations is strongly dependent on the phosphine that is employed (see scheme). Moreover, synthesized vinylcyclopentenes can be easily transformed into cycloheptadiene derivatives through a carboncarbon allylic bond cleavage.