Thiazole-based synthesis of C-glycosyl aldehydes

Article abstract of DOI:10.1016/S0040-4039(00)79319-1

The formylation at the anomeric carbon of the model sugars 2,3,4,6-tetra-O-benzyl-D-glucopyranose and 2,3:5,6-di-O-isopropylidene-D-mannofuranose is carried out by addition of 2-lithiothiazole to the corresponding lactones followed by reductive dehydroxyl