Design, synthesis and antimuscarinic activity of some imidazolium derivatives

Article abstract of DOI:10.1016/S0960-894X(99)00517-X

A series of imidazolium salt derivatives was prepared as part of a search for subtype-selective antimuscarinic agents. On the basis of measurements of the antimuscarinic activity and subtype-selectivity for M₂ and M₃ muscarinic receptors, the structure-activity relationships of these compounds are discussed.