Synthesis of 3-Trifluoromethylfurans from β,β-Bis(trifluoromethyl) α,β-Unsaturated Ketones and Tin(II) Chloride

DOI: 10.1039/c39920000348

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 348 - 349 (1992)

Update date:2022-08-04

Topics:

Authors:

Burger, Klaus

Helmreich, Brigitte

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39920000348

A new building block strategy for the syntheisi of 3-trifluoromethyl-substituted furans 9 and 10 is described from β,β-bis(trifluoromethyl) α,β-unsaturated ketones 2 via reductive fluoride elimination and 1,5-electrocyclization with elimination.

Full text of DOI:10.1039/c39920000348

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:Furan, 2-fluoro-5-(4-methylphenyl)-3-(trifluoromethyl)-

Cas No:140860-86-2

R&D Labs maybe for 140860-86-2

Dalian Join King Biochemical Tech. Co., Ltd.

Contact:0411 39216206

Address:814 First State Blvd
Shanghai Gsyn Chemical Co.,Ltd.

Contact:86-021-67158290

Address:86-021-67158291
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
KAIYUAN CHEMICAL COMPANY LIMITED.

website:http://www.kaiyuanchem.com

Contact:+86-22-59891255/66/77

Address:B-2205, Kuangshi International Building, Yingbin Road, XiangLuo Bay Business District, Binhai New area, Tianjin, China.
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China

Relevant to this article

Design and synthesis of potent antitumor 5,4'-diaminoflavone derivatives based on metabolic considerations

Doi:10.1021/jm9700326
(1997)
Living ring-opening homo- and copolymerisation of ε-caprolactone and l-lactide by cyclic β-ketiminato aluminium complexes

Doi:10.1039/c3dt52712c
(2014)
CARBAMOYLMETHYL GROUP AS AN ACTIVATED GROUP IN PROTEASE- AND BASE-CATALYZED TRANSESTERIFICATION OF 1,4-DIHYDROPYRIDINES: A NOVEL ASYMMETRIC SYNTHESIS OF VALNIDIPINE

Doi:10.1016/S0040-4039(00)73813-5
(1993)
Structure-based design of an acyclic ligand that bridges FKBP12 and calcineurin

Doi:10.1021/ja00075a092
(1993)
General and functional group-tolerable approach to allenylsilanes by rhodium-catalyzed coupling between propargylic carbonates and a silylboronate

Doi:10.1021/ol902339a
(2009)
Synthetic approaches to either homochiral or achiral derivatives of 3-hydroxy-2(5H)-furanone (isotetronic acid)

Doi:10.1016/S0040-4020(01)81841-X
(1993)

Article Doi