Nucleophilic Addition of 2-Indolylacyl Anion Equivalents to N-Alkylpyridinium Salts

DOI: 10.1021/jo00036a015

Source and publish data:

Journal of Organic Chemistry p. 2835 - 2841 (1992)

Update date:2022-08-04

Topics:

Authors:

Bennasar, M.-Lluisa

Zulaica, Ester

Bosch, Joan

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Article abstract of DOI:10.1021/jo00036a015

The reactions of the anions derived from dithioacetals 1-3 and α-amino nitriles 4 toward pyridinium salts 5 are studied.Depending on the nucleophile used, 2-(dihydropyridylmethyl)indoles 6 and 7, which can be cyclized to tetracyclic methanoazocinindole systems 10 and 11, respectively, or 2-substituted 3-(dihydropyridyl)indoles 8 and 9 are formed.

Full text of DOI:10.1021/jo00036a015

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