Preparation of Polyfunctional Allenic Alcohols by the Regioselective Addition of Functionalized Propargylic Chromium(III) Organometallics to Carbonyl Compounds

DOI: 10.1021/jo00041a006

Source and publish data:

Journal of Organic Chemistry p. 4070 - 4074 (1992)

Update date:2022-07-30

Topics:

Authors:

Belyk, Kevin

Rozema, Michael J.

Knochel, Paul

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00041a006

The reaction of propargylic halides 1 (X = Cl, Br) with an aldehyde or ketone (0.67 equiv) in the presence of CrCl2 (2.0 equiv) and LiI (2 equiv, necessary if X = Cl) affords allenic alcohols 3 with excellent regioselectivities (3-6percent of the regioiso

Full text of DOI:10.1021/jo00041a006

Products guided by the article

Product name:2-butyl-1-cyclohexyl-2,3-butadien-1-ol

Cas No:141375-85-1

R&D Labs maybe for 141375-85-1

Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.

Contact:86-532-88250866

Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China
Shreeji pharma international

Contact:0091-265-2313036

Address:311, ATLANTIS HEIGHTS SARABHAI MAIN ROAD,VADIWADI ,VADODARA
Luoyang Aoda chemical Co.,Ltd.

Contact:+86-379-67518785 67516588

Address:MiaoWan industry district,YanShi City,Henan,China
Tianjin Tensing Fine Chemical Research Develop Centre

Contact:86-022-23718576,13032267585

Address:2-2-201,13 Guiyuan road,Huayuan Industry district,Tianjin,china
jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china

Relevant to this article

Reactivity enhancement of a diphosphene by reversible N-heterocyclic carbene coordination

Doi:10.1039/c8sc00348c
(2018)
Iodine-mediated α-acetoxylation of 2,3-disubstituted indoles

Doi:10.1021/ol302983t
(2012)
Three-component reaction of propargyl amines, sulfonyl azides, and alkynes: One-pot synthesis of tetrasubstituted imidazoles

Doi:10.1021/ol303023y
(2012)
Synthesis of 2,5-Disubstituted Oxazoles from Arylacetylenes and α-Amino Acids through an i ₂ /Cu(NO ₃) ₂ ?3H ₂ O-Assisted Domino Sequence

Doi:10.1055/s-0037-1612087
(2019)
Iridium-catalyzed asymmetric hydrogenation of α-substituted α,β-unsaturated acyclic ketones: Enantioselective total synthesis of (-)-mesembrine

Doi:10.1021/ol302842h
(2012)
(E)-N′-(4-Chlorobenzylidene)-,(E)-N′-(4-bromobenzylidene)- and (E)-N′-[4-(diethylamino)benzylidene]-derivatives of 4- hydroxybenzohydrazide

Doi:10.1107/S0108270112038462
(2012)

Article Doi