Synthesis and optical resolution of an antiallergic agent KW4099 with thromboxane A2 antigonistic activity

DOI: 10.1248/cpb.40.238

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 238 - 239 (1992)

Update date:2022-07-30

Topics:

Authors:

Sugaya Sugaya

Kuge Kuge

Tomioka Tomioka

Tamaki Tamaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.238

A new antiallergic agent with thromboxane A₂ antagonistic activity, KW4099, was synthesized by a simple method. Its optical resolution was accomplished with the use of (+)- or (-)-2,2'-(1,1'-binaphthyl)phosphoric acid as a resolving agent.

Full text of DOI:10.1248/cpb.40.238

NII-Electronic Library Service

Products guided by the article

Product name:sodium (-)-11-<2-(4-benzyl-1-piperidinyl)ethyl>thio-6,11-dihydrodibenzoxepine-2-carboxylate

Cas No:141423-67-8

R&D Labs maybe for 141423-67-8

Nanjing Habo Medical Technology Co., Ltd.

Contact:025－85769882

Address:No.108. Ganjiabian east. Qixia District .Nanjing
Hebei Tianxiang Biological & Pharmaceutical Co., Ltd

Contact:86-0312-6615158

Address:No 42 fazhan street qingyuan county
suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China
ShangHai Soyoung Biotechnology Inc

website:http://www.soyoungbio.com

Contact:+86-21-69893009

Address:shanghai
Nanjing HuiBaiShi Biotechnology Co.,Ltd.

Contact:+86 (25)58745219

Address:No.606 Ningliu Road,LiuHe District.

Relevant to this article

Cyclometalated phenylquinoline rhodium complexes as protein kinase inhibitors

Doi:10.1016/j.ica.2012.04.035
(2012)
Synthesis and biological activity of NK-1 selective, N-backbone cyclic analogs of the C-terminal hexapeptide of substance P

Doi:10.1021/jm960154i
(1996)
Stereospecific Synthesis of the Top-Half Precursor to the Antitumor Agent Vinblastine and a Simple Bisindole Analogue.

Doi:10.1016/S0040-4039(00)91570-3
(1992)
Discovery of a series of novel compounds with moderate anti-avian H5N1 influenza virus activity in chick embryo

Doi:10.1007/s00044-012-0341-2
(2013)
Synthesis and Glutathione Peroxidase-like activity of N-heterocyclic carbene derived cationic diselenides

Doi:10.1016/j.tet.2012.09.024
(2012)
Metal derivatives of N¹-substituted thiosemicarbazones: Synthesis, structures and spectroscopy of nickel(II) and cobalt(III) complexes

Doi:10.1016/j.ica.2012.09.021
(2013)

Article Doi