Journal of Medicinal Chemistry p. 2321 - 2327 (1992)
Update date:2022-08-05
Topics:
Thornton
Jackman
Marsham
O'Connor
Bishop
Calvert
The synthesis of a series of new C2-methyl-N10-alkylquinazoline-based thymidylate synthase (TS) inhibitors containing difluorinated p-aminobenzoate rings is described. Derivatives of the N10-propargyl and N10- m
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