Synthesis of the Aziridinopyrrolidine Substructure of the Antitumor Agents Azinomycin A and B

DOI: 10.1021/jo00048a006

Source and publish data:

Journal of Organic Chemistry p. 5813 - 5815 (1992)

Update date:2022-08-03

Topics:

Authors:

Coleman, Robert S.

Carpenter, Andrew J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00048a006

A stereoselective synthesis of the central aziridino<1,2-a>pyrrolidine substructure (19) of the antitumor agents azinomycin A and B is reported and featured as the key step an intramolecular Michael addition-elimination reaction between the aziridine and

Full text of DOI:10.1021/jo00048a006

Products guided by the article

Product name:methyl 2--2-deoxy-4,6-O-(4-methoxybenzylidene)-α-D-glucopyranoside

Cas No:141438-52-0

R&D Labs maybe for 141438-52-0

Antaeus Bio-technology Co., LTD(expird)

Contact:021-31252569

Address:shanghai pudong
shanghai tuomiao chemicial co.,ltd.

website:https://www.tuomiaochem.com/

Contact:021 - 59853336

Address:shanghai
Nantong Chem-land Co., Ltd.

Contact:86 513 85512619

Address:Rm.1306, Building A, Wenfeng Mansion,168 Gongnong Road, Nantong Jiangsu China
Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China

Relevant to this article

Solid-phase synthesis of 4,7,8-trisubstituted 1,2,3,4-tetrahydro-benzo[e] [1,4]diazepin-5-ones

Doi:10.1021/co300121d
(2012)
Chiral Diels-Alder reaction between cyclopentadiene and nitroso derivatives: Thermal isomerisation/racemisation of the adducts

Doi:10.1016/j.tetasy.2012.09.005
(2012)
Rhodium-catalyzed decarbonylation cross-coupling reactions of aromatic aldehydes and arylboronic acids via C–C bond activation directed by a guide group chelation

Doi:10.1016/j.inoche.2020.108065
(2020)
Direct assembly of 3,4-difunctionalized benzofurans and polycyclic benzofurans by phenol dearomatization and palladium-catalyzed domino reaction

Doi:10.1002/anie.201404155
(2014)
Synthesis of γ-fluoroalkylated allylic amines derivatives via palladium-catalyzed Overman rearrangement

Doi:10.1016/j.tetlet.2012.10.045
(2012)
Electrogenerated base-promoted synthesis of 5-aryl-5,6-dihydro-2H-pyrano[2,3-d]pyrimidine-2,4,7-triones by multicomponent assembly of barbituric acid, aldehydes and Meldrum's acid at room temperature

Doi:10.1039/c4ra08251f
(2014)

Article Doi