C. Xie et al. / Tetrahedron Letters 53 (2012) 6650–6653
6653
O
O
O
O
O
the first cycle
the second cycle
deprotection/Michael
O
O
O
N
N
N
deprotection/Michael
N
Ph
N
N
Ph
Ph
3aa
4aa
N
(DBU)
N
(DBU)
O
O
O
O
O
Cat-COCH3
N
N
N
Ph
O
N
1A
O
O
Cat
O
N
2D
N
N
Ph
N
Ph
2A
O
O
O
O
O
O
O
N
N
O
O
O
N
O
Ph
1B
O
N
Ph
1C1
N
N
Ph
1C2
N
N
N
N
Ph
N
N
2C
Ph
Ph
2B
1C3
Scheme 3. Proposed Mechanism of the reaction.
Palazzino, G.; Filacchioni, G.; Martini, C.; Giannaccini, G.; Lucacchini, A. J.
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and the Fundamental Research Funds for the Central Universities
(No. 1107020522 and No. 1082020502). The Jiangsu 333 program
(for Pan) and Changzhou Jin-Feng-Huang program (for Han) are
also acknowledged.
Supplementary data
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Melani, F.; Palazzino, G.; Filacchioni, G. Tetrahedron Lett. 1987, 28, 5165–5168;
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