ASYMMETRIC SYNTHESIS OF PIPERIDINE ALKALOIDS UTILIZING DIASTEREOSELECTIVE REACTION OF 1,3-OXAZOLIDINE WITH GRIGNARD REAGENTS

DOI: 10.3987/COM-91-S1

Source and publish data:

Heterocycles p. 17 - 20 (1992)

Update date:2022-09-26

Topics:

Authors:

Higashiyama, Kimio

Nakahata, Keiji

Takahashi, Hiroshi

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Article abstract of DOI:10.3987/COM-91-S1

A facile method of synthesizing enantiomerically pure piperidine alkaloids, (R)-(-)-coniine and (2R,6S)-(-)-dihydropinidine, has been explored by employing the highly diastereoselective reaction of a 1,3-oxazolidine with Grignard reagents.

Full text of DOI:10.3987/COM-91-S1

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