An Intramolecular Diels-Alder/Retro-Mannich Approach to the cis-Perhydroquinoline Ring System. Model Studies toward the Synthesis of Lycopodium Alkaloids

Article abstract of DOI:10.1021/jo00041a011

Model studies toward the preparation of cis-decahydroquinoline derivatives using an IMDA/retro-Mannich strategy were carried out.Tricyclic amino ester 13, prepared via an IMDA reaction of 1,2-dihydropyridine 11, was ring-opened on treatment with excess LD