Archiv der Pharmazie p. 193 - 198 (1992)
Update date:2022-08-03
Topics:
Demotes-Mainard
Tranchot
Cambar
Jarry
A series of 5-dialkylaminomethyl-2-amino-2-oxazolines was prepared and screened for diuretic activity. These compounds were previously examined for their lipophilic behaviour using a reversed-phase HPLC technique. The capacity factors, expressed as log k'w, were correlated with the partition coefficient log P. A QSAR analysis of the diuretic activity in relation with the lipophilicity was attempted for these structurally related compounds.
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Doi:10.1007/s00044-012-0382-6
(2013)Doi:10.1016/j.ejmech.2013.10.041
(2013)Doi:10.1021/ja310909q
(2013)Doi:10.1016/S0040-4039(00)74167-0
(1992)Doi:10.1007/s00044-012-0400-8
(2013)Doi:10.1021/acs.jmedchem.0c01773
(2022)
