Canadian Journal of Chemistry p. 43 - 50 (2013)
Update date:2022-08-05
Topics:
Li, Pan
Wu, Chunrui
Zhao, Jingjing
Li, Yang
Xue, Weichao
Shi, Feng
Aryne [3 + 2] cycloaddition with nitrones generated in situ from the addition of hydroxylamines to acetylenedicarboxylates affords moderate to good yields of dihydrobenzisoxazoles. This reaction extends the current scope of aryne cycloaddition to include in situ generated nitrones and produces functionalized dihydrobenzisoxazoles with a quaternary center.
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