Tetrahedron p. 377 - 382 (1987)
Update date:2022-08-02
Topics:
Bonjoch, Josep
Casamitjana, Nuria
Quirante, Josefina
Torrens, Antoni
Paniello, Anna
Bosch, Joan
An improved method for the synthesis of 4-azatricyclo(5.2.2.04,8)undecan-11-one (1) is reported.The synthesis involves hydrogenolysis of 8-hydroxyethyl-2-azabicyclo(3.3.1)nonan-7-one 3 followed by intramolecular alkylation of the resulting seco
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