Tetrahedron p. 3131 - 3138 (1992)
Update date:2022-07-30
Topics: Synthesis Characterization Yield Ketone Derivatization Aryl group Purification Catalysis Reaction Optimization Alkyl group
Bonjoch, Josep
Casamitjana, Nuria
Quirante, Josefina
Garriga, Carmer
Bosch, Joan
Two approaches to 8-alkyl-8-aryl-2-azabicyclo[3.3.1]nonan-7-ones are explored. They are based on the cyclization of an α-alkyl α-aryl ketone upon an iminium salt generated from 2-cyanopiperidine 13 and on the arylation of 8-alkyl-2-azabicyclo[3.3.1]nonan-
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Doi:10.1021/om00043a013
(1992)Doi:10.1246/bcsj.71.685
(1998)Doi:10.1016/j.saa.2012.10.037
(2013)Doi:10.1021/ol303479f
(2013)Doi:10.1021/om301121x
(2013)Doi:10.1016/j.bmcl.2012.10.107
(2013)
