Reactions of trifluoromethyl ketones. VIII. Investigation of steric effects of a trifluoromethyl group through ene reaction of trifluoromethyl ketones

DOI: 10.1248/cpb.40.593

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 593 - 598 (1992)

Update date:2022-08-02

Topics:

Authors:

Nagai Nagai

Nishioka

Koyama Koyama

Ando Ando

Miki Miki

Kumadaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.593

In the course of our study on the ene reaction of trifluoromethyl ketones, a trifluoromethyl group has been observed to behave as a larger substituent than commonly believed in the biomedicinal field. To estimate the steric eflect of a trifluoromethyl gro

Full text of DOI:10.1248/cpb.40.593

NII-Electronic Library Service

Products guided by the article

Product name:1-butyl-1-(trifluoroacetyl)cyclohexane

Cas No:141779-30-8

R&D Labs maybe for 141779-30-8

BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA
Lanzhou huibang biological chemical technology Co., LTD

Contact:0931-7843964

Address:NO.2011,Yannan Road,Chengguan,
Guangxi Nanning Guangtai Agriculture Chemical Co.,Ltd

Contact:+86-771-2311266

Address:Room703,Building12, Software Park Phase II,NO.68,Keyuan Road,Nanning City,Guangxi,China
Jurong Huaheng Natural Biological Products Factory

website:http://www.risebiochem.com

Contact:+86-13921007726

Address:Chuncheng town,Jurong city,Jiangsu province,China
Weifang Yukai Chemical Co.,Ltd.

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china

Relevant to this article

Bi^III-corroles: A versatile platform for the synthesis of functionalized corroles

Doi:10.1002/ejic.201200697
(2012)
Enzyme-substrate complementarity governs access to a cationic reaction manifold in the P450_BM3-catalysed oxidation of cyclopropyl fatty acids

Doi:10.1002/chem.201203035
(2012)
Asymmetric synthesis of conformationally constrained L-AP4 analogues using chiral sulfinyl auxiliary

Doi:10.1016/j.tet.2012.10.085
(2013)
Synthesis of a new pH-sensitive folate-doxorubicin conjugate and its antitumor activity in vitro

Doi:10.1002/jps.23381
(2013)
Synthesis of various 3'-branched 2',3'-unsaturated pyrimidine nucleosides as potential anti-HIV agents

Doi:10.1021/jo00052a057
(1992)
(Acyloxy)alkoxy moiety as amino acids protecting group for the synthesis of (R,R)-2,7 diaminosuberic acid via RCM

Doi:10.2174/092986612803521666
(2012)

Article Doi