
Tetrahedron Letters p. 2391 - 2394 (1992)
Update date:2022-08-04
Topics:
Royo
Garcia-Echeverria
Giralt
Eritja
Albericio
A new acid stable protecting group for the sulfhydryl function of cysteine is described. The S-2-(2,4-dinitrophenyl)ethyl-L-cysteine derivative is fully compatible with the Boc/Bzl solid-phase peptide synthesis strategy and can be smoothly and quantitatively removed to give the free thiol or a disulfide bridge.
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