First synthesis of 5,6,7,8-tetrahydro-8-deaza-8-thiafolic acid

DOI: 10.1248/cpb.40.49

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 49 - 52 (1992)

Update date:2022-08-04

Topics:

Authors:

Sako Sako

Totani Totani

Hirota Hirota

Maki Maki

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Article abstract of DOI:10.1248/cpb.40.49

5,6,7,8-Tetrahydro-8-deaza-8-thiafolic acid (3) was synthesized as a diastereoisomeric mixture via thermal condensation of 5-hydroxyisocytosine (6) with diethyl N-[p-(2-amino-3-mercaptopropyl)aminobenzoyl]glutamate (10) after activation of the C(6)-positi

Full text of DOI:10.1248/cpb.40.49

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Product name:N²,N₅-dibenzoyl-6-ethoxycarbonyl-5,6,7,8-tetrahydro-8-deaza-8-thiapterin

Cas No:142109-10-2

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