Design, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infections

Article abstract of DOI:10.1080/15257770008033000

Stereoselective glycosylation of 2,5,6-trichlorobenzimidazole (1b), 2- bromo-5,6-dichlorobenzimidazole (1c), 5,6-dichlorobenzimidazole (1d), 5,6- dichlorobenzimidazole-2-thione (1e), 5,6-dichloro-2-(methylthio)benzimidazole (1f), 2-(benzylthio)-5,6-dichlo

Full text of DOI:10.1080/15257770008033000

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Design, Synthesis, and Antiviral
Evaluation of 2-Deoxy-D-Ribosides of
Substituted Benzimidazoles as Potential
Agents for Human Cytomegalovirus
Infections
Ruiming Zou a b , Etsuko Kawashima a c , George A. Freeman a d
George W. Koszalka a d , John C. Drach a & Leroy B. Townsend a
a Department of Medicinal Chemistry, College of Pharmacy;
,
Department of Chemistry, College of Literature, Sciences and Arts;
Department of Biologic and Materials Sciences , School of Dentistry,
University of Michigan , Ann Arbor, MI, 48109-1065, USA
b Gilead Sciences , 344 Lakeside Drive, Foster City, California, 94404
c Tokyo University of Pharmacy and Life Science , 1432-1 Horinouchi,
Hachioji, Tokyo, JAPAN
d Glaxo Wellcome, Inc. , Five Moore Drive, Research Triangle Park,
NC, 27709
Published online: 24 Sep 2006.
To cite this article: Ruiming Zou , Etsuko Kawashima , George A. Freeman , George W. Koszalka ,
John C. Drach & Leroy B. Townsend (2000) Design, Synthesis, and Antiviral Evaluation of 2-Deoxy-D-
Ribosides of Substituted Benzimidazoles as Potential Agents for Human Cytomegalovirus Infections,
Nucleosides, Nucleotides and Nucleic Acids, 19:1-2, 125-153, DOI: 10.1080/15257770008033000
To link to this article: http://dx.doi.org/10.1080/15257770008033000
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