Chemoenzymatic Enantiocontrolled Synthesis of (-)-Specionin

DOI: 10.1021/jo00043a037

Source and publish data:

Journal of Organic Chemistry p. 4740 - 4746 (1992)

Update date:2022-07-29

Topics:

Authors:

Hudlicky, Tomas

Natchus, Michael

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Article abstract of DOI:10.1021/jo00043a037

Specionin acetate 1a has been synthesized from chlorobenzene in 15 steps and compared with an authentic sample.The chirality was incorporated into the synthesis by microbial dioxygenation of chlorobenzene using a mutant strain of Pseudomonas putida, 39D,

Full text of DOI:10.1021/jo00043a037

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