Chemoenzymatic Enantiocontrolled Synthesis of (-)-Specionin

Article abstract of DOI:10.1021/jo00043a037

Specionin acetate 1a has been synthesized from chlorobenzene in 15 steps and compared with an authentic sample.The chirality was incorporated into the synthesis by microbial dioxygenation of chlorobenzene using a mutant strain of Pseudomonas putida, 39D,