Catalytic Asymmetric Synthesis of Quarternary Carbon Centers. Palladium-Catalyzed Formation of Either Enantiomer of Spirooxindoles and Related Spirocyclics Using a Single Enantiomer of a Chiral Diphosphine Ligand

DOI: 10.1021/jo00043a005

Source and publish data:

Journal of Organic Chemistry p. 4571 - 4572 (1992)

Update date:2022-07-30

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Authors:

Ashimori, Atsuyuki

Overman, Larry E.

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Article abstract of DOI:10.1021/jo00043a005

The asymmetric synthesis of eight spirooxindoles and related spirocyclics from the corresponding aryl iodide by palladium catalyzed cyclizations in the presence of the diphosphine ligand (R)-(+)-BINAP is reported.

Full text of DOI:10.1021/jo00043a005

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