Catalytic Asymmetric Synthesis of Quarternary Carbon Centers. Palladium-Catalyzed Formation of Either Enantiomer of Spirooxindoles and Related Spirocyclics Using a Single Enantiomer of a Chiral Diphosphine Ligand

DOI: 10.1021/jo00043a005

Source and publish data:

Journal of Organic Chemistry p. 4571 - 4572 (1992)

Update date:2022-07-30

Topics:

Authors:

Ashimori, Atsuyuki

Overman, Larry E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00043a005

The asymmetric synthesis of eight spirooxindoles and related spirocyclics from the corresponding aryl iodide by palladium catalyzed cyclizations in the presence of the diphosphine ligand (R)-(+)-BINAP is reported.

Full text of DOI:10.1021/jo00043a005

Products guided by the article

Product name:(R)-(+)-1'-benzyl-1',2'-dihydro-2'-oxospiro[1,4-dioxaspiro[4.5]dec-6-ene-8,3'-3'H-indole]

Cas No:142613-67-0

R&D Labs maybe for 142613-67-0

Suns Chemical Sdn Bhd

Contact:0086 371 65711996

Address:Jalan 4/3, Kawasan Perindustrian Serendah, 48000 Rawang,
Dongtai Xinyuan Chemical Co., Ltd.

Contact:+86-21-56733000

Address:404F, 99Nong No.117 Zhongtan Rd. Shanghai
Hangzhou J&H Chemical Co., Ltd.

website:http://www.jhechem.com/

Contact:+86-571-87396432

Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China
Ningbo Distant Chemicals Co.,Ltd

Contact:86-574-27862490,27862438

Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
TIANJIN ZHONGXIN CHEMTECH CO.,LTD.

Contact:86-022-89880739

Address:10B, Pan China International Center, No. 931 YingKou Road, TangGu, Tianjin, China, 300451

Relevant to this article

Diastereoselective synthesis of 1,3- Syn -oxazines via a tandem hemiaminalization and Tsuji-Trost reaction

Doi:10.1055/s-0032-1318300
(2013)
Iron-catalyzed N-alkylation using π-activated ethers as electrophiles

Doi:10.1039/c3ob27128e
(2013)
Diastereoselective synthesis of enantiopure γ-butenolide- butyrolactones towards Pseudopterogorgia lactone furanocembranoid substructures

Doi:10.1055/s-0032-1317555
(2012)
Sulfoximine directed intermolecular o-C-H amidation of arenes with sulfonyl azides

Doi:10.1021/ol400411v
(2013)
Total synthesis of gelsemiol

Doi:10.1002/chem.201203746
(2013)
Epidithiodiketopiperazine as a pharmacophore for protein lysine methyltransferase G9a inhibitors: Reducing cytotoxicity by structural simplification

Doi:10.1016/j.bmcl.2012.11.087
(2013)

Article Doi