N-Alkoxycarbonyl Amino Acid N-Carboxyanhydrides and N,N-Dialkoxycarbonyl Amino Acid Fluorides from N,N-Diprotected Amino Acids

DOI: 10.1039/c39920000812

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Journal of the Chemical Society. Chemical communications p. 812 - 813 (1992)

Update date:2022-08-02

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Authors:

Savrda, J.

Wakselman, M.

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Article abstract of DOI:10.1039/c39920000812

Activation of N,N-bis-Boc or N-Boc N-Z amino acids with SOCl2-DMF leads to N-protected N-carboxy amino acid anhydrides, whereas treatment with cyanuric fluoride at low temperature gives mainly N,N-bis-protected amino acid fluorides, which are efficient ac

Full text of DOI:10.1039/c39920000812

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