Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 2. Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine

DOI: 10.1016/S0040-4020(01)89666-6

Source and publish data:

Tetrahedron p. 3905 - 3914 (1994)

Update date:2022-08-02

Topics:

Authors:

Akiba, Toshifumi

Tamura, Osamu

Hashimoto, Masaru

Kobayashi, Yuko

Katoh, Tadashi

et al. et al.

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Article abstract of DOI:10.1016/S0040-4020(01)89666-6

The title synthesis was achieved by featuring diastereoface-selective cyclopropanation of (4R,5S)-4,5-diphenyl-3-vinyl-2-oxazolidinone and its related compounds, the chiral conformationally rigid N-vinylcarbamates, with zinc-monofluorocarbenoid, followed

Full text of DOI:10.1016/S0040-4020(01)89666-6

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Product name:(4R,5S)-3-((1R,2R)-2-Fluoro-cyclopropyl)-4,5-diphenyl-oxazolidin-2-one

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