Stereoselective Synthesis of Highly Substituted γ-Lactones by Diastereoselective Alkylation of (α-Benzenesulfonyl) Derivatives with Unusual Facial Selectivity

DOI: 10.1021/jo00105a027

Source and publish data:

Journal of Organic Chemistry p. 8081 - 8091 (1994)

Update date:2022-09-26

Topics: Stereoselective synthesis Diastereoselective alkylation Facial selectivity

Authors:

Rodriguez, Carmen M.

Martin, Tomas

Ramirez, Miguel A.

Martin, Victor S.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00105a027

The oxidation of α-(phenylthio) γ-lactones obtained by the base-induced cyclization of enantiomerically enriched γ-<(phenylthio)acyl>-α,β-unsaturated esters to sulfones in those cases where the α-carbon has an available proton and further basic alkylation

Full text of DOI:10.1021/jo00105a027

Products guided by the article

Product name:Methyl (2R,3R,4S)-<4-(benzenesulfonyl)-4-butyl-5-oxo-2-propyltetrahydrofuran-3-yl>acetate

Cas No:142968-34-1

R&D Labs maybe for 142968-34-1

Acorn PharmaTech Co., Ltd

Contact:86-25-58619180

Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China
Tianjin Boron PharmaTech Co.,Ltd.(expird)

Contact:86-022-59845187

Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
GLD peptide scientific lnc.

Contact:21-7631221 15884421033

Address:326 Science and technology,Shanghai,China
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.

Contact:15967177856

Address:Genglou Industrial Development Area
WUHAN WELLSONG INT'L CO.,LTD

Contact:+86-27-85733560

Address:NO.308,QINGNIAN RD.,WUHAN,CHINA

Relevant to this article

Synthesis and structure-activity relationship of thiobarbituric acid derivatives as potent inhibitors of urease

Doi:10.1016/j.bmc.2014.05.057
(2014)
Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents

Doi:10.1016/j.ejmech.2013.09.009
(2013)
Porphyrin Donor and Tunable Push–Pull Acceptor Conjugates—Experimental Investigation of Marcus Theory

Doi:10.1002/chem.201700043
(2017)
Electron-rich N-heterocyclic silylene (NHSi)-iron complexes: Synthesis, structures, and catalytic ability of an isolable hydridosilylene-iron complex

Doi:10.1021/ja402480v
(2013)
Reversible phase transition of 4-ethoxybenzenammonium iodide

Doi:10.1002/zaac.201200406
(2013)
Salt Effects on Proton Transfer from Nitrophenols to Amine or Pyridine Bases in Acetonitrile

Doi:10.1021/j100045a020
(1995)

Article Doi