A new synthesis of 2-aryloxypropionic acids derivatives via selective mono-C-methylation of methyl aryloxyacetates and aryloxyacetonitriles with dimethyl carbonate

DOI: 10.1016/0040-4020(95)00718-N

Source and publish data:

Tetrahedron p. 11573 - 11580 (1995)

Update date:2022-07-29

Topics:

Authors:

Bomben, Andrea

Marques, Carlos A.

Selva, Maurizio

Tundo, Pietro

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Article abstract of DOI:10.1016/0040-4020(95)00718-N

A one-pot procedure for the mono-C-methylation of methyl aryloxyacetates and aryloxyaceto nitriles by dimethyl carbonate (DMC) is reported. The reaction is carried out in an autoclave at high temperatures (180-200°C) and in the presence of a base (K₂

Full text of DOI:10.1016/0040-4020(95)00718-N

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