Asymmetric multipoint control by palladium-catalyzed diastereoselective tandem carbon-carbon bond formation

Article abstract of DOI:10.1016/S0040-4039(00)92674-1

Palladium-catalyzed diastereo-differentiative tandem connection of cis-alkenyl iodide, cyclic fragment, and terminal acetylene was executed. The discrimination of the diastereotopic face and olefinic carbons of norbornene was achieved with accompanying isomerization of the cis-geometry of the olefin to trans in good yields.