C9-imino and C10-amino derivatives of ascomycin (21-ethyl-FK 506)

DOI: 10.1016/S0040-4039(00)74800-3

Source and publish data:

Tetrahedron Letters p. 3845 - 3846 (1992)

Update date:2022-09-26

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Authors:

Nussbaumer, Peter

Grassberger, Maximilian

Schulz, Gerhard

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Article abstract of DOI:10.1016/S0040-4039(00)74800-3

Treatment of Ascomycin (21-ethyl-FK 506) with ammonia in alcoholic solution yeilds C9-imine 5 and C10-amine 6, whereas methylamine gives only C9-methylimine 10.

Full text of DOI:10.1016/S0040-4039(00)74800-3

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