Synthesis and biological activity of 17-chloro-16(17) unsaturated D-homo antiprogestins

DOI: 10.1016/0039-128X(94)90024-8

Source and publish data:

Steroids p. 176 - 180 (1994)

Update date:2022-07-29

Topics:

Authors:

Schwede, Wolfgang

Cleve, Arwed

Neef, Guenter

Ottow, Eckhard

Stoeckemann, Klaus

Wiechert, Rudolf

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0039-128X(94)90024-8

An efficient approach to 17-chloro-16(17) unsaturated D-homo antiprogestins is described.The key steps of the synthesis are a ring-expansion via dichlorocarbene addition to a 17-silyl enol ether and a palladium catalyzed coupling of an 11β-(4-aryltriflate

Full text of DOI:10.1016/0039-128X(94)90024-8

Products guided by the article

Product name:17-chloro-3,3-<1,2-ethanediylbis(oxy)>-17aα-(1-propynyl)-11β-<4-<<(trifluoromethyl)sulfonyl>oxy>phenyl>-17a-homo-5α-estr-16-en-5,17aβ-diol

Cas No:143611-09-0

R&D Labs maybe for 143611-09-0

Zibo HaiDing chemical plant

Contact:13864437655

Address:Zibo city, shandong province Zhang Dian award and industrial park HaiDing chemical plant
zhuzhou zhongle chemical co. ltd.

Contact:+86-0731 28228409

Address:Zhuzhou, Hunan, China
ChangZhou XiaQing Chemical Co., Ltd.

Contact:+86-519-88721665

Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province，China
SHAANXI TOP PHARM CHEMICAL CO.LTD

Contact:+86-029-85733403

Address:No.108 ,west sector,south er huan,xi'an,china
Xi'an caijing Opto-Electrical Science & Technology Co., LTD

Contact:+86-29-88294447

Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China

Relevant to this article

Intramolecular benzannulation reactions of manganese carbene complexes

Doi:10.1021/ja00048a076
(1992)
Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies

Doi:10.1016/j.ejmech.2016.01.046
(2016)
Template control over dimerization and guest selectivity of interpenetrated coordination cages

Doi:10.1021/ja403184a
(2013)
A facile method for the synthesis of pyridazino[4,5-b][1,4]thiazine-diones via Smiles rearrangement

Doi:10.1016/j.tetlet.2013.04.026
(2013)
Ambi-valence taken literally: Ruthenium vs iron oxidation in (1,1′-diphosphinoferrocene)ruthenium(II) hydride and chloride complexes as deduced from spectroelectrochemistry of the heterodimetallic mixed-valent intermediates

Doi:10.1021/om1004258
(2010)
A new archaeal β-glycosidase from Sulfolobus solfataricus: Seeding a novel retaining β-glycan-specific glycoside hydrolase family along with the human non-lysosomal glucosylceramidase GBA

Doi:10.1074/jbc.M109.086470
(2010)

Article Doi