Synthesis and biological activity of 17-chloro-16(17) unsaturated D-homo antiprogestins

DOI: 10.1016/0039-128X(94)90024-8

Source and publish data:

Steroids p. 176 - 180 (1994)

Update date:2022-07-29

Topics:

Authors:

Schwede, Wolfgang

Cleve, Arwed

Neef, Guenter

Ottow, Eckhard

Stoeckemann, Klaus

Wiechert, Rudolf

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0039-128X(94)90024-8

An efficient approach to 17-chloro-16(17) unsaturated D-homo antiprogestins is described.The key steps of the synthesis are a ring-expansion via dichlorocarbene addition to a 17-silyl enol ether and a palladium catalyzed coupling of an 11β-(4-aryltriflate

Full text of DOI:10.1016/0039-128X(94)90024-8

Products guided by the article

Product name:17-chloro-3,3-<1,2-ethanediylbis(oxy)>-17aα-(1-propynyl)-11β-<4-<<(trifluoromethyl)sulfonyl>oxy>phenyl>-17a-homo-5α-estr-16-en-5,17aβ-diol

Cas No:143611-09-0

R&D Labs maybe for 143611-09-0

AstaTech ( Chengdu) BioPharmaceutical Corp.

website:http://www.astabiochem.cn/

Contact:+86-15198215156-15198215156

Address:SICHUAN CHENGDU
Springchem New Material Technology Co.,Limited

website:http://www.spring-chem.com

Contact:86-21-62885108

Address:602B, Building 1, No. 641, Tianshan Road
shanghai jinshan pharmaceutical Co.,Ltd

Contact:021-57363011，13681638167

Address:No. 7966 Tingfeng Road,Jinshan,Shanghai,China
Luna Chemicals Co.,Ltd.

Contact:+86-570-4336358

Address:No.87 Building,Tianqian,Sidu Town
Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101

Relevant to this article

Intramolecular benzannulation reactions of manganese carbene complexes

Doi:10.1021/ja00048a076
(1992)
Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies

Doi:10.1016/j.ejmech.2016.01.046
(2016)
Template control over dimerization and guest selectivity of interpenetrated coordination cages

Doi:10.1021/ja403184a
(2013)
A facile method for the synthesis of pyridazino[4,5-b][1,4]thiazine-diones via Smiles rearrangement

Doi:10.1016/j.tetlet.2013.04.026
(2013)
Ambi-valence taken literally: Ruthenium vs iron oxidation in (1,1′-diphosphinoferrocene)ruthenium(II) hydride and chloride complexes as deduced from spectroelectrochemistry of the heterodimetallic mixed-valent intermediates

Doi:10.1021/om1004258
(2010)
A new archaeal β-glycosidase from Sulfolobus solfataricus: Seeding a novel retaining β-glycan-specific glycoside hydrolase family along with the human non-lysosomal glucosylceramidase GBA

Doi:10.1074/jbc.M109.086470
(2010)

Article Doi