Simple synthesis of the 5-O-benzoylriboside of 1,4-dihydronicotinic acid; A cofactor for DT diaphorase and nitroreductase enzymes

Article abstract of DOI:10.1080/15257779508012369

A simple one flask synthesis of the 5 O-benzoylriboside and riboside of nicotinic acid has been developed. Reduction of the benzoylriboside with sodium dithionite gives the 1,4-dihydronicotinic acid in good yield.

Full text of DOI:10.1080/15257779508012369

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Nucleosides and Nucleotides
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Simple Synthesis of the 5-O-
Benzoylriboside of 1,4-Dihydronicotinic
Acid; a Cofactor for DT Diaphorase and
Nitroreductase Enzymes
Lawrence C. Davies a
a Cancer Research Campaign Laboratory , CRC Centre for Cancer
Therapeutics at The Institute of Cancer Research , 15 Cotswold
Road, Sutton, Surrey, SM2 5NG, UK
Published online: 16 Feb 2007.
To cite this article: Lawrence C. Davies (1995) Simple Synthesis of the 5-O-Benzoylriboside of 1,4-
Dihydronicotinic Acid; a Cofactor for DT Diaphorase and Nitroreductase Enzymes, Nucleosides and
Nucleotides, 14:3-5, 311-312
To link to this article: http://dx.doi.org/10.1080/15257779508012369
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