
Chemical and Pharmaceutical Bulletin p. 1663 - 1668 (1996)
Update date:2022-08-04
Topics:
Kudo, Noriaki
Furuta, Satoru
Sato, Kazuo
The reaction of methyl 2-chloro-5-ethoxycarbonylamino-4-fluorobenzoate (4a) and 1-bromo-3,3-dimethyl-2-butanone (2) in the presence of 2.2 eq of lithium bis(trimethylsilyl)amide afforded the 4H-1,4-benzoxazine (6a) in good yield instead of the expected 4-
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