Journal of Medicinal Chemistry p. 4230 - 4237 (1992)
Update date:2022-09-26
Topics:
Georg
Cheruvallath
Himes
Mejillano
Burke
Taxol (1) is a highly potent antitumor agent, exerting its mechanism of action by promoting the assembly of stable microtubules in cells. We are reporting on the first synthesis and biological evaluation of taxol derivatives with substituted phenyl rings
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