Structural features of substituted purine derivatives compatible with depletion of human O6-alkylguanine-DNA alkyltransferase

DOI: 10.1021/jm00101a028

Source and publish data:

Journal of Medicinal Chemistry p. 4486 - 4491 (1992)

Update date:2022-09-26

Topics:

Authors:

Moschel Moschel

McDougall

Dolan Dolan

Stine Stine

Pegg Pegg

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Article abstract of DOI:10.1021/jm00101a028

A series of O⁶- and S⁶-substituted purine derivatives were tested for their ability to deplete the human DNA repair protein O⁶-alkylguanine-DNA alkyltransferase (AGT) in cell-free extracts from HT29 colon tumor cells and i

Full text of DOI:10.1021/jm00101a028

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